Abstract
Tissue loss of the nostrils presents a considerable surgical challenge due to the
greatly reduced availability of local tissue within such a peculiar anatomical region.
The traditional reconstructive methods, such as direct suture, secondary healing,
skin grafts, and local skin flaps, have shown poor provision of desirable cosmetic
outcomes in this area. The authors propose an innovative and alternative method of
cosmetic reconstruction of small skin defects of the nostril based on a hyaluronan-induced
skin regeneration. Such a procedure allowed the healing of relatively large areas
of skin loss with the formation of a truly regenerated tissue whose clinical features
closely resemble those of the local normal skin. Nevertheless, the proposed procedure
is lengthy and time-consuming and requires high levels of cooperation from patients.
In our practice, the hyaluronan-induced skin regeneration is now considered the first
choice for cosmetic reconstruction of small defects of the nostril in needy patients.
Keywords
nostril reconstruction - hyaluronan - skin regeneration - wound healing
